Prevalence of Vitamin B12 Deficiency in Type 2 Diabetes Mellitus

Abstract

Vitamin B₁₂ named as Cobalamin a water-soluble vitamin plays significant role in several biological process such as DNA synthesis, Neurological function, and Optimal Haemopoiesis etc. The deficiency of vitamin B₁₂ affects a number of processes, including the methylation of homocysteine, nucleoprotein, myelin production, DNA synthesis, lipid and glucose metabolism, and others. Vitamin B₁₂ deficiency is a potential comorbidity that is often overlooked, but puts many diabetic patients at risk of developing particular complications. Various research showing an association between type 2 diabetes mellitus and a vitamin B₁₂ deficiency. The purpose of the study is to find out the prevalence of vitamin B₁₂ deficiency in Type 2 diabetic patients. 200 subjects of Type 2 diabetic patients were studied over a period of six months from August 2023 to February 2024 in the OPD of Kaya Chikitsha, Department of Ayurveda, IMS, Banaras Hindu University, Varanasi. Results: The present study summarizes that the prevalence of vitamin B₁₂ deficiency in T₂DM patients were 19% and 36% of respondents has borderline vitamin B₁₂ level. The results also shows that the majority of male were having the deficiency of the vitamin B₁₂ level as compare to the females. Study also shows the association of age and the vitamin B_12­ level (p<0.05).